Neutralization of IL-28A/IL-28B in HepG2 human hepatocellular carcinoma cell line. Samples were incubated in IL-28A/IL-28B monoclonal antibody (Product # MA5-23902). Recombinant Mouse IL‚28B/IFN‚λ3 reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the HepG2 human hepatocellular carcinoma cell line in a dose-dependent manner (orange line). Inhibition of EMCV activity elicited by Recombinant Mouse IL‚28B/IFN‚λ3 (400 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse IL‚28B/IFN‚λ3 Monoclonal Antibody. The ND50 is typically 3-9 µg/mL.